Homoleptic Copper(I) Arylthiolates as a New Class of p-Type Charge Carriers: Structures and Charge Mobility Studies.
Polymeric homoleptic copper(I) arylthiolates [Cu(p-SC(6)H(4)-X)](infinity) (X=CH(3) (1), H (2), CH(3)O (3), tBu (4), CF(3) (5), NO(2) (6), and COOH (7)) have been prepared as insoluble crystalline solids in good yields (75-95 %). Structure determinations by powder X-ray […]
Spotlights on our sister journals: Chem. Eur. J. 10/2008.
Dielectrophoretic Trapping of DNA Origami.
Kuzyk A, Yurke B, Toppari JJ, Linko V, Törmä P.
Nanoscience Center, Department of Physics, University of Jyväskylä, P.O. Box 35, FIN-40014 (Finland).
Surface Functionalized Carbogenic Quantum Dots.
Bourlinos AB, Stassinopoulos A, Anglos D, Zboril R, Karakassides M, Giannelis EP.
Institute of Materials Science, NCSR “Demokritos†Ag. Paraskevi Attikis, Athens 15310 (Greece).
Sequence-Addressable DNA Logic.
Voelcker NH, Guckian KM, Saghatelian A, Ghadiri MR.
Departments of Chemistry and Molecular Biology and The Skaggs Institute for Chemical Biology The Scripps Research Institute 10550 North Torrey Pines Road La Jolla, CA 92037 (USA).
Alterations of the IKBKG locus and diseases: an update and a report of 13 novel mutations.
Mutations in the inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), also called nuclear factor-kappaB (NF-kB) essential modulator (NEMO), gene are the most common single cause of incontinentia pigmenti (IP) in females and […]
K45R variant of squalene synthase increases total cholesterol levels in two study samples from a French Canadian population.
Squalene synthase is an important component of the cholesterol biosynthetic pathway, and inhibitors of this enzyme have been shown to lower plasma cholesterol levels. Previously, we sequenced the squalene synthase gene, FDFT1 (farnesyl-diphosphate farnesyltransferase), and […]
Characterisation of murine MICL (CLEC12A) and evidence for an endogenous ligand.
Inhibitory receptors are required for the control of cellular activation and they play essential roles in regulating homeostasis and immunity. We previously identified a human inhibitory C-type lectin-like receptor, MICL (CLEC12A), a heavily glycosylated monomer predominantly expressed on myeloid cells. Here we […]
Sequential phases in the development of Aire-expressing medullary thymic epithelial cells involve distinct cellular input.
Intrathymic deletion of immature thymocytes that express self-reactive TCR specificities is essential in the generation of self tolerance. Medullary thymic epithelial cells (mTEC) expressing the transcriptional regulator Aire play a key role in this process by regulating expression […]
AMP-activated protein kinase regulates lymphocyte responses to metabolic stress but is largely dispensable for immune cell development and function.
AMP-activated protein kinase (AMPK), a phylogenetically conserved serine/threonine protein kinase, represents an energy sensor able to adapt cellular metabolism in response to nutritional environmental variations. TCR stimulation activates AMPK, a regulatory event that is […]
