Archive for March, 2008

Age-related macular degeneration and low-vision rehabilitation: a systematic review.

Age-related macular degeneration and low-vision rehabilitation: a systematic review.
Background: Because of the prevalence and devastating consequences of age-related macular degeneration (AMD), a systematic review devoted to low-vision rehabilitation and AMD seems timely and appropriate. Methods: Several electronic databases were searched for studies from 1980 to 2006 involving individuals with low vision or […]

Blepharitis: current strategies for diagnosis and management.

Blepharitis: current strategies for diagnosis and management.
Background: The aim of this article is to present a consensus on the appropriate identification and management of patients with blepharitis based on expert clinical recommendations for 4 representative case studies and evidence from well-designed clinical trials.Methods: The case study recommendations were developed at a consensus […]

The Boston Keratoprosthesis in severe ocular trauma.

The Boston Keratoprosthesis in severe ocular trauma.
Background: In eyes with corneal disease and opacity so severe that standard corneal transplantation carries a poor prognosis, a keratoprosthesis (KPro) may still be successful in providing functional visual acuity. The purpose of this study was to determine the outcome of Boston KPro implantation in the […]

Cyclops.

Cyclops.
Steinbach MJ.

Circulating uveal melanoma cells: should we test for them? / Devrait-on faire un test de détection

Circulating uveal melanoma cells: should we test for them? / Devrait-on faire un test de détection des cellules métastatiques circulantes du mélanome de l\’uvée ?
Fernandes BF, Belfort RN, Di Cesare S, Burnier MN Jr.

Keratoprosthesis in the treatment of severe ocular trauma / La kératoprothèse dans le traitement d

Keratoprosthesis in the treatment of severe ocular trauma / La kératoprothèse dans le traitement d\’un grave traumatisme oculaire.
Aquavella JV.

The roles of MAPKs in disease.

The roles of MAPKs in disease.
MAP kinases transduce signals that are involved in a multitude of cellular pathways and functions in response to a variety of ligands and cell stimuli. Aberrant or inappropriate functions of MAPKs have now been identified in diseases ranging from cancer to inflammatory disease to obesity and diabetes. […]

Migratory properties of cultured olfactory ensheathing cells by single-cell migration assay.

Migratory properties of cultured olfactory ensheathing cells by single-cell migration assay.
Olfactory ensheathing cells (OECs) are a unique type of glial cells that have axonal growth-promoting properties. OEC transplantation has emerged as a promising experimental therapy of axonal injuries and demyelinating diseases. However, some fundamental cellular properties of OECs remain unclear. In this […]

Cost-effectiveness of pharmacogenetic testing to tailor smoking-cessation treatment.

Cost-effectiveness of pharmacogenetic testing to tailor smoking-cessation treatment.
We evaluated the cost-effectiveness of a range of smoking cessation drug treatments, including varenicline, transdermal nicotine (TN), bupropion and the use of a genetic test to choose between TN and bupropion. We performed Monte Carlo simulation with sensitivity analysis, informing analyses with published estimates of […]

Interaction between polymorphisms in the renin-angiotensin-system and angiotensin-converting enzyme

Interaction between polymorphisms in the renin-angiotensin-system and angiotensin-converting enzyme inhibitor or beta-blocker use and the risk of myocardial infarction and stroke.
This study investigates whether the interaction between angiotensin-converting enzyme (ACE) inhibitors or beta-blockers and the ACE insertion/deletion (I/D) polymorphism or angiotensin receptor II type 1 (AGTR1) 573C/T polymorphism modifies the risk of […]