Archive for March, 2008

The impact of nutritional and exercise strategies for aging bone and muscle.

The impact of nutritional and exercise strategies for aging bone and muscle.
This symposium addressed recent evidence suggesting that nutritional intervention and resistance-training strategies may be important for aging bone and muscle. The physiological consequences of aging and the potential mechanistic actions of nutritional aids during resistance training were emphasized.
Candow DG.
Faculty […]

Vascular nitric oxide: effects of exercise training in animals.

Vascular nitric oxide: effects of exercise training in animals.
Exercise training is known to induce several adaptations in the cardiovascular system, one of which is increased skeletal muscle blood flow at maximal exercise. Improved muscle blood flow, in turn, could in part be accounted for by augmented endothelium-dependent, nitric oxide (NO)-mediated vasodilation. Studies […]

Vascular biology of angiotensin and the impact of physical activity.

Vascular biology of angiotensin and the impact of physical activity.
The renin-angiotensin system (RAS) is important for regulating blood pressure and extracellular fluid. The concept of the RAS has recently evolved from a classical systemic endocrine system to an appreciation of local RASs functioning in a paracrine manner, including in the vascular wall. […]

Nitric oxide and muscle blood flow in exercise.

Nitric oxide and muscle blood flow in exercise.
Despite being the subject of investigation for well over 100 years, the nature of exercising muscle blood flow control remains, in many respects, poorly understood. In this review we focus on the potential role of nitric oxide in vasodilation of muscle resistance vessels during a […]

Introduction to proceedings from the 2005 CSEP symposium “Exercise and the endothelium&amp

Introduction to proceedings from the 2005 CSEP symposium “Exercise and the endothelium”
This introduction summarizes the topics addressed in the three companion review papers on various issues surrounding exercise and the endothelium. Leading experts in the field discuss the most recent findings regarding the following: (i) nitric oxide and exercise hyperemia, (ii) the […]

Book review / Critique de livre.

Book review / Critique de livre.
Shephard RJ.

The role of protein-mediated transport in regulating mitochondrial long-chain fatty acid oxidation.

The role of protein-mediated transport in regulating mitochondrial long-chain fatty acid oxidation.
This thesis is an investigation of the role of fatty acid translocase (FAT/CD36), plasma membrane associated fatty acid binding protein (FABPpm), and carnitine palmitoyltransferase I (CPTI) in transporting long-chain fatty acids (LCFAs) across mitochondrial membranes. Maximal CPTI activity, as well as […]

Determinants of VO2 max decline with aging: an integrated perspective.

Determinants of VO2 max decline with aging: an integrated perspective.
Aging is associated with a progressive decline in the capacity for physical activity. Central to this decline is a reduction in the maximal rate of oxygen utilization, or VO2 max. This critical perspective examines the roles played by the factors that determine the […]

Muscling in on microarrays.

Muscling in on microarrays.
Adaptations that are the result of exercise require a multitude of changes at the level of gene expression. The mechanisms involved in regulating these changes are many, and can occur at various points in the pathways that affect gene expression. The completion of the human genome sequence, along with […]

Are functional foods redefining nutritional requirements?

Are functional foods redefining nutritional requirements?
Functional foods are increasing in popularity owing to their ability to confer health and physiological benefits. Nevertheless, the notion that functional foods improve health when providing nutrients at levels above and beyond existing recommended intakes is inconsistent with the definition of requirement. This disparity highlights the need […]