[Autosomal dominant polycystic kidney disease: from genes to cilium.]
[Autosomal dominant polycystic kidney disease: from genes to cilium.]
Autosomal dominant polycystic kidney disease (ADPKD) is a quite frequent monogenic hereditary disease. The incidence has been reported to range between 1:400 and 1:1000 life births. The disease is caused by a mutation of the PKD1 gene in 85% of the cases and by […]