Deletion of the first pair of fibronectin type III repeats of the integrin beta-4 gene is associated with epidermolysis bullosa, pyloric atresia and aplasia cutis congenita in the original Carmi syndrome patients.
Birnbaum RY, Landau D, Elbedour K, Ofir R, Birk OS, Carmi R.
The Morris Kahn Laboratory of Human Genetics, Soroka University […]
Revisiting metatropic dysplasia: Presentation of a series of 19 novel patients and review of the literature.
Metatropic dysplasia (MD-OMIM: 156530 and 250600) is a rare chondrodysplasia characterized by short limbs with limitation and enlargement of joints and usually severe kyphoscoliosis, first described in 1893. Up until now, 81 other patients have been reported. […]
The effects of erdosteine, N-acetylcysteine, and vitamin E on nicotine-induced apoptosis of hippocampal neural cells.
This study investigated the frequency of apoptosis in rat hippocampal neural cells after intraperitoneal nicotine injection, examining the roles of the inflammatory markers myeloperoxidase (MPO) and tumor necrosis factor alpha (TNF-alpha) in nicotine-induced brain damage and the protective […]
Differential regulation of HSP70 expression by the JNK kinases SEK1 and MKK7 in mouse embryonic stem cells treated with cadmium.
JNK, a member of the mitogen-activated protein kinases (MAPKs), is activated by the MAPK kinases SEK1 and MKK7 in response to environmental stresses. In the present study, the effects of CdCl(2) treatment on […]
Non-invasive analysis of cell cycle dynamics in single living cells with Raman micro-spectroscopy.
Raman micro-spectroscopy is a laser-based technique which enables rapid and non-invasive biochemical analysis of cells and tissues without the need for labels, markers or stains. Previous characterization of the mammalian cell cycle using Raman micro-spectroscopy involved the analysis of suspensions […]
Studying immunity at the whole organism level.
Little TJ, Colegrave N, Sadd BM, Schmid-Hempel P.
Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, EH9 3JT, UK.
Reply to Drs Little, Colegrove, Sadd and Schimd-Hempel.
Hauton C, Smith V.
School of Ocean and Earth Science, University of Southampton, National Oceanography Centre, European Way, Southampton SO14 3ZH, United Kingdom.
Regulation of mammalian gene expression by retroelements and non-coding tandem repeats.
Genomes of higher eukaryotes contain abundant non-coding repeated sequences whose overall biological impact is unclear. They comprise two categories. The first consists of retrotransposon-derived elements. These are three major families of retroelements (LINEs, SINEs and LTRs). SINEs are clustered in gene-rich regions […]
It\’s not random anymore.
Caporale LH.
Judith P. Sulzberger, MD Genome Center, Columbia University, 1150 St. Nicholas Avenue Room 504, New York, NY 10032.
On the development of neural diversity in the brain.
The FEBS meeting titled \”Generating neural diversity in the brain\” took place on the island of Capri, from October 13-16. This high-level workshop was the 20(th) in a symposium series organized by the IGB (Instituto Genetica et Biophysica) of Naples funded by international agencies […]
