Medical Library

Changes in calcium-dependent membrane permeability properties in mitochondria of livers from arthritic rats.
The involvement of the mitochondrial permeability transition pore (PTP) in the responses of mitochondria from adjuvant-induced arthritic rats to Ca(2+) addition was investigated. The respiratory activity, the Ca(2+)-induced osmotic swelling and the electrophoretic (45)Ca(2+) uptake were evaluated in the absence […]

Characterization of RNA-binding proteins possibly involved in modulating human AT(1) receptor mRNA stability.
Angiotensin II exerts its cardiovascular effects mainly through the activation of AT(1) receptors. These receptors can be regulated at a post-transcriptional level, that is through the modulation of the mRNA stability. This regulation usually involves proteins which are able to […]

Silicon nanotechnologies of pigmented heterokonts.
Many pigmented heterokonts are able to synthesize elements of their cell walls (the frustules) of dense biogenic silica. These include diatom algae, which occupy a significant place in the biosphere. The siliceous frustules of diatoms have species-specific patterns of surface structures between 10 and a few hundred nanometers. […]

BimEL-dependent apoptosis induced in peripheral blood lymphocytes with n-butyric acid is moderated by variation in expression of c-myc and p21(WAF1).
We have examined the effect of sodium butyrate (SB) on the viability of normal peripheral blood lymphocytes (PBLs) in vitro and the effect of this agent on the expression of 20 apoptosis-related genes. […]

Developmental changes in the relationship between leptin and adiposity among Tsimané children and adolescents.
Leptin is thought to signal energy stores, thus helping the body balance energy intake and expenditure. However, the strong relationship between leptin and adiposity in populations with adequate nutrition or common obesity is not universal across ecologic contexts, and […]

Low digit ratio (2D:4D) is associated with delayed menarche.
The prenatal environment of the human fetus is now known to have lasting physiological and behavioral effects into childhood and adulthood. The objective of this study was to examine the relationship between early testosterone exposure, as measured by the ratio of the length of […]

Energy expenditure among farmers in developing countries: What do we know?
The trend toward overweight and obesity in developing countries is often assumed to be due, in part, to reductions in energy expenditure associated with the transition from agrarian to urban lifestyles. In this article we first review the published studies on energy […]

Relation of ratio indices of anthropometric measures to obesity in a stunted population.
The ratios of anthropometric measures are used to estimate obesity while controlling for allometric scaling. A good index should be uncorrelated with its denominator; this often requires exponentiation of the denominator. The stability of the derived exponents across populations is […]

Rural urban differences of cardiovascular disease risk factors in adult Asian Indians.
The prevalence of cardiovascular disease (CVD) risk factors in \”People of Indian Origin\” (PIO) is exceedingly high and strong relationships among elevated blood pressure, increased levels of lipoproteins, visceral obesity, physical inactivity and subsequent high occurrence of coronary heart disease, type […]

Selective antiaggressive effect of an alpha-2 adrenoceptor agonist naphthylmedetomidine in mice.
Alpha-2 adrenoceptors (alpha(2)-ARs) are critically involved in regulating neurotransmitter release from sympathetic nerves and neurons and play an important role in the regulation of awareness, arousal and vigilance. In our recent study, dexmedetomidine, a full alpha(2)-AR agonist, produced antiaggressive effects in the […]