Regio- and diastereo-selectivity of montmorillonite-catalyzed oligomerization of racemic adenosine 5
Regio- and diastereo-selectivity of montmorillonite-catalyzed oligomerization of racemic adenosine 5\’-phosphorimidazolide.
Clay is a possible candidate for an effective catalyst in prebiotic chemical evolution of biomolecules. Montmorillonite was reported to effectively catalyze oligomerization of racemic adenosine 5\’-phosphorimidazolide (DL-ImpA). In the oligomerization reaction, considerable amounts of cyclic dimers as well as linear dimers were produced in the oligomerization reactions. To assess the regio- and diastereo-selectivities of the oligomerization reaction, the dimer products including cyclic dimers were completely identified by means of enzymatic degradation reactions of the products.
Urata H, Fujimori M, Aono C, Yamakawa T, Harada E, Akagi M.
Osaka University of Pharmaceutical Sciences, Osaka, Japan.